Per Diem Nursing Jobs in Spartanburg, South Carolina
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Working as a nurse in Spartanburg
Spartanburg sits at the heart of South Carolina’s Upstate, just east of Greenville, with a healthcare community that creates consistent demand for nurses and CNAs. From acute care hospitals to skilled nursing, rehabilitation, and senior-living facilities across Boiling Springs, Duncan, and the surrounding area, Spartanburg offers a wide mix of settings for RNs, LPNs, and CNAs.
Spartanburg Regional Healthcare System is one of the largest employers in the region, and along with Prisma Health and a network of skilled nursing and assisted living communities, it keeps per diem opportunities available throughout the week.
South Carolina is a Nurse Licensure Compact (NLC) state. If you hold a qualifying multistate RN or LPN license from another compact state, you can practice in South Carolina without applying for a separate South Carolina license. CNAs must meet South Carolina certification requirements.
With Switch, you browse available shifts, choose when you work, and get paid quickly — giving you more control over your schedule and your income.
About Spartanburg
Part of the greater Greenville–Spartanburg metro, Spartanburg is known for its historic downtown, growing manufacturing base, and college community. Its steady healthcare demand makes it a strong market for nurses and CNAs looking for flexible per diem shifts close to home.
Nursing pay in Spartanburg, South Carolina
RNs working per diem in the Spartanburg area are paid $40–$40/hr, LPNs $36–$36, and CNAs $20–$20 (Switch — rates paid on completed shifts, last 12 months).
Figures are the middle 50% of hourly rates actually paid to providers on completed Switch shifts over the last 12 months, including weekend and holiday premiums. Rates vary by facility and shift — you’ll see the exact rate on every shift before you claim it. As a 1099 provider you cover self-employment tax and benefits.
What nurses actually earn in Spartanburg, South Carolina
Switch rates are what providers were actually paid on completed shifts over the past year — not a starting rate. Shown against local wages for employed staff nurses.
| Role | Switch (1099 per diem) | Local staff wages (W-2) |
|---|---|---|
| CNA | $20/hr top shifts to $22.50 | $18–$19/hr |
| LPN | $36/hr top shifts to $40.50 | $28–$35/hr |
| RN | $40/hr | $34–$41/hr |
Switch figures are the middle 50% of hourly rates actually paid on completed shifts in the last 12 months, including weekend and holiday premiums; “top shifts” is the 95th percentile. Local staff wages are employed (W-2) hourly ranges from the U.S. Bureau of Labor Statistics, May 2025. As a 1099 provider you cover self-employment tax and benefits, so the two figures are not directly equivalent.
Jobs by role in Spartanburg, South Carolina
- CNA Jobs in Spartanburg, South Carolina
- LPN Jobs in Spartanburg, South Carolina
- RN Jobs in Spartanburg, South Carolina
Nearby markets
What nurses say about Switch
“Working for Switch has been a wonderful experience and has also been empowering for a busy mom like myself. I have the privilege to pick and choose my own schedule and work around my hectic schedule outside of work as a parent.”
“I have been with Switch for about five years now and the thing that I like the best about them is because they care about their workers. They pay me quickly, which is a good thing. Being with Switch brings me peace of mind. Great agency to work for!”
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FAQs about working in Spartanburg
Does Switch have shifts across Spartanburg?
Yes. Switch connects clinicians with opportunities throughout the Spartanburg area, including Boiling Springs, Duncan, Greer, and nearby Upstate communities as facilities become available.
Do I need a South Carolina nursing license to work per diem shifts in Spartanburg?
South Carolina is part of the Nurse Licensure Compact (NLC). If you hold a qualifying multistate RN or LPN license from another compact state, you can generally work in South Carolina without a separate South Carolina license. CNAs must hold a valid South Carolina certification before accepting shifts.
How much do per diem nurses and CNAs make in Spartanburg?
Pay varies by role, experience, facility type, and demand. Weekend, holiday, and high-demand shifts often pay more. With Switch, you’ll always see the exact pay before you accept a shift.
Can I pick up shifts around a full-time job or nursing school?
Yes. Many RNs, LPNs, and CNAs use Switch to add income around a full-time position, nursing school, or family life, with no minimum-hour requirements. You choose which shifts fit your schedule.